Endometriosis resections are often the first step towards improving the quality of life and fertility of affected patients. However, postoperative adhesions can jeopardize these treatment goals. Two consecutive publications by Krämer et al. (2021 & 2023) provide important insights into how the risk of adhesions can be reduced and what this means for patients – with impressive results.

Publication 1: Adhesion prevention after endometriosis surgery (2021)
A randomized, controlled study investigated how effectively the 4DryField® PH adhesion barrier can prevent postoperative adhesions. The results speak for themselves:
✅ 85% fewer adhesions and
✅ significantly fewer affected areas (53%)
compared to the control group

But what does this reduction mean in practical terms for patients?

Publication 2: Long-term follow-up on pain & fertility (2023)
A one-year follow-up of patients showed significant clinical improvements:
✅ Pregnancy rate almost tripled – a significant advantage for patients who wish to have children after endometriosis resection
✅ Reduction in pain parameters (5 types of pain that can occur in the pelvis were examined, such as menstrual pain, pain unrelated to the menstrual cycle or pain when going to the toilet, etc.)

Why is this relevant?
The studies by Krämer et al. show impressively that adhesion barriers not only prevent adhesions, but can also help to improve the quality of life of patients in terms of pain and fertility

The full publication of the studies summarized above can be found here:
Krämer et al. (2021): Adhesion prevention after endometriosis surgery – results of a randomized, controlled clinical trial with secondlook laparoscopy
Krämer et al. (2023): Improvement in Fertility and Pain after Endometriosis Resection and Adhesion Prevention with 4DryField® PH: Follow-up of a Randomized Controlled Clinical Trial

This article is part of the series “Optimizing endometriosis surgery: Avoiding adhesions, improving quality of life”. Follow us on LinkedIn for more!